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Paul A Gleeson Selected Research

H(+)-K(+)-Exchanging ATPase (Hydrogen, Potassium ATPase)

7/2014Helios defines T cells being driven to tolerance in the periphery and thymus.
6/2014Transient systemic inflammation does not alter the induction of tolerance to gastric autoantigens by migratory dendritic cells.
1/2011A convenient model of severe, high incidence autoimmune gastritis caused by polyclonal effector T cells and without perturbation of regulatory T cells.
8/2007Prevention of autoimmune gastritis in mice requires extra-thymic T-cell deletion and suppression by regulatory T cells.
2/2006CD4+CD25+ regulatory T cells inhibit the antigen-dependent expansion of self-reactive T cells in vivo.
10/2004Growth factors associated with gastric mucosal hypertrophy in autoimmune gastritis.
10/2002Immunopathogenesis, loss of T cell tolerance and genetics of autoimmune gastritis.
9/2002Endogenous H/K ATPase beta-subunit promotes T cell tolerance to the immunodominant gastritogenic determinant.

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Paul A Gleeson Research Topics

Disease

12Gastritis
01/2017 - 09/2002
6Alzheimer Disease (Alzheimer's Disease)
01/2021 - 09/2011
5Autoimmune Diseases (Autoimmune Disease)
05/2013 - 10/2002
3Inflammation (Inflammations)
01/2020 - 06/2014
3Amyloid Plaque
01/2019 - 09/2011
2Hypertrophy
01/2011 - 10/2004
1Carcinogenesis
01/2021
1Neuroinflammatory Diseases
01/2020
1Hemophilia B (Haemophilia B)
01/2018
1Neoplasm Metastasis (Metastasis)
11/2011
1Neurodegenerative Diseases (Neurodegenerative Disease)
09/2011
1Infections
06/2006
1Hypertrophic Gastritis (Giant Hypertrophic Gastritis)
10/2004

Drug/Important Bio-Agent (IBA)

8H(+)-K(+)-Exchanging ATPase (Hydrogen, Potassium ATPase)IBA
07/2014 - 09/2002
6AutoantigensIBA
07/2014 - 10/2002
6Adenosine Triphosphatases (ATPase)IBA
07/2014 - 10/2002
5Amyloid (Amyloid Fibrils)IBA
01/2020 - 09/2011
4Proteins (Proteins, Gene)FDA Link
01/2019 - 09/2013
4Peptides (Polypeptides)IBA
01/2019 - 09/2011
3AntigensIBA
01/2017 - 10/2008
2CytokinesIBA
01/2020 - 06/2006
2Amyloid Precursor Protein Secretases (beta-Secretase)IBA
01/2016 - 09/2013
2AutoantibodiesIBA
01/2011 - 10/2004
1CholesterolIBA
01/2021
1Mechanistic Target of Rapamycin Complex 1IBA
01/2021
1Amyloid beta-PeptidesIBA
01/2020
1Factor IX (Coagulation Factor IX)FDA LinkGeneric
01/2018
1AlbuminsIBA
01/2018
1EnzymesIBA
01/2016
1Peptide Hydrolases (Proteases)FDA Link
01/2016
1DNA (Deoxyribonucleic Acid)IBA
06/2014
1Immunosuppressive Agents (Immunosuppressants)IBA
05/2013
1Adrenal Cortex Hormones (Corticosteroids)IBA
05/2013
1Proton Pumps (Proton Pump)IBA
11/2008
1Polysaccharides (Glycans)IBA
10/2008
1EpitopesIBA
10/2008
1Membrane Proteins (Integral Membrane Proteins)IBA
11/2005
1RNA (Ribonucleic Acid)IBA
10/2004
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
10/2004
1LigandsIBA
10/2004
1GastrinsIBA
10/2004
1ErbB Receptors (EGF Receptor)IBA
10/2004
1Messenger RNA (mRNA)IBA
10/2004
1AmphiregulinIBA
10/2004

Therapy/Procedure

1Therapeutics
12/2006